2014年9月4日星期四

Diabetic nephropathy patients receiving dialysis prone to problems

Dialysis patients with diabetic nephropathy and non-diabetic dialysis patients symptoms, such as hypotension was 20%, 50% hypertension, nausea, and vomiting twice a control. Hypotension and autonomic dysfunction, especially orthostatic hypotension; even tachycardia, cardiac arrest.

Dialysis patients because of blood glucose, plasma osmolality decreased, can produce hypotension. Applications sugar-free dialysate may stimulate gluconeogenesis and glycogen breakdown, leading to a negative nitrogen balance. Dialysate, of course, can also cause high blood sugar, so it should not be applied. Prevention of complications in patients with dialysis method comprising: inputting, mannitol, sodium resolve high oxygen, loss of colloidal solutions, or vasoactive drugs with no pre-dialysis blood pressure taking hypertensive medication. In dialysis patients should limit sodium and fluid intake, control of blood glucose and blood pressure.

There is a wide range of patients with diabetic vascular disease, fistula complications, such as side to side anastomosis of blood syndrome often causes distal ischemia, severe gangrene and amputation produce, so it should end anastomosis or distal artery ligation fistula. Requiring emergency dialysis, you can use a temporary or peritoneal dialysis catheter through.

Peripheral vascular disease is common in diabetic patients with peripheral vascular disease, is two times the puncture site infection in diabetic patients. It is reported that 33% of diabetic patients without a pulse, 1/15 of the person requiring amputation.

Diabetic vascular disease is characterized by a plurality of segments and spread the invasion, so the higher amputation rate. The incidence of diabetes in patients with cerebral vascular disease and cerebrovascular atherosclerosis, thrombosis than non-diabetic patients 2 times. Every 10 dialysis patients with diabetes occurred one case of cerebral hemorrhage or cerebral thrombosis. Violations of cardiovascular disease in diabetic vascular disease large blood vessels and capillaries, due to the clinical symptoms of coronary heart disease, can also be asymptomatic. 52 cases of diabetes autopsy material showed hyperplasia and subcutaneous fibrosis in 72% of small artery intimal thickening of atherosclerosis transparent protein deposition.

Among diabetic patients on dialysis obtain more than 50% of patients without diabetes. Hyperglycemia have been reported in diabetic ESRD patients due to pulmonary edema can lead to rapid changes in interstitial fluid chamber. Therefore, dietary restriction and control of the patient is very important in water, but for diabetic patients, is more difficult.

Dialysis patients with diabetes increased prevalence of infection resulting in death, is two-fold diabetes. Therefore, dialysis patients with diabetes is more important to comply with aseptic.

Diabetic nephropathy bone bone disease seems lighter than diabetic nephropathy bone disease, its cause is unknown. Patients with diabetic nephropathy serum parathyroid hormone concentrations lower than the same serum calcium levels in diabetic patients.

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