Kidney Cancer Linked to Kidney Stones

A kidney stone is a hard object that is made from chemicals in the urine. But can be found at any point in your urinary tract. The urinary tract includes the kidneys, ureters, bladder, and urethra. Not all kidney stones are made up of the same crystals.

Patients with a history of kidney stones are at significantly higher risk of renal cell carcinoma (RCC) and transitional cell carcinoma (TCC), according to the findings of a meta-analysis presented at the 2014 Kidney Week meeting.

The meta-analysis, by Wisit Cheungpasitporn, MD, of Mayo Clinic in Rochester, Minn., and colleagues, included 7 studies. A history of kidney stones was associated with a significant 76% increased risk of RCC and a 2.1 times increased risk of TCC.

In subgroup analyses, the risk of RCC associated with stones was significant only in male subjects. The researchers concluded that their findings may impact clinical management and cancer surveillance. Our kidney disease hospital email kidneyhospitalabroad@hotmail.com

Extended Hemodialysis May Improve Phosphate Control

Since the 1960s, when hemodialysis first became a practical treatment for kidney failure, we've learned much about how to make hemodialysis treatments more effective and minimize side effects.  Hemodialysis can be an outpatient or inpatient therapy. Routine hemodialysis is conducted in a dialysis outpatient facility, either a purpose built room in a hospital or a dedicated, stand alone clinic.

Extended treatment time (TT) on hemodialysis (HD) may improve serum phosphate control, according to study findings presented at the 2014 Kidney Week meeting.

Investigators at Imperial College Hospital NHS Trust and North Bristol NHS Trust in the U.K. compared extended TT (6 hours) and standard TT (4 hours) on HD in a randomized, crossover study that included 29 patients. During the extended TT phase of the study, serum phosphate decreased significantly from 1.67 g/dL before treatment to 1.27 g/dL after 6 hours of treatment.

During the standard TT phase, serum phosphate increased significantly from 1.51 g/dL before treatment to 1.94 g/dL after 4 hours of treatment.

In addition, during the standard TT phase, researchers observed a significant increase in extracellular water, whereas during the extended TT phase, patients had no significant change in hydration status.

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