Extended Hemodialysis May Improve Phosphate Control

Since the 1960s, when hemodialysis first became a practical treatment for kidney failure, we've learned much about how to make hemodialysis treatments more effective and minimize side effects.  Hemodialysis can be an outpatient or inpatient therapy. Routine hemodialysis is conducted in a dialysis outpatient facility, either a purpose built room in a hospital or a dedicated, stand alone clinic.

Extended treatment time (TT) on hemodialysis (HD) may improve serum phosphate control, according to study findings presented at the 2014 Kidney Week meeting.

Investigators at Imperial College Hospital NHS Trust and North Bristol NHS Trust in the U.K. compared extended TT (6 hours) and standard TT (4 hours) on HD in a randomized, crossover study that included 29 patients. During the extended TT phase of the study, serum phosphate decreased significantly from 1.67 g/dL before treatment to 1.27 g/dL after 6 hours of treatment.

During the standard TT phase, serum phosphate increased significantly from 1.51 g/dL before treatment to 1.94 g/dL after 4 hours of treatment.

In addition, during the standard TT phase, researchers observed a significant increase in extracellular water, whereas during the extended TT phase, patients had no significant change in hydration status.

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