What are the effects of high blood pressure, kidney disease?

Pressure renal arteriolar sclerosis) and malignant arteriolar nephrosclerosis, accompanied by corresponding clinical manifestations of the disease.
A diagnostic 】 【, history and symptoms
Age more than in 40 ~ 50 years of age or older, hypertension 5 ~ 10 years. Early night urine increased, only then appear proteinuria, individual cases can occur due to the broken capillaries of transient with macroscopic haematuria, but without obvious low back pain. Often merge arteriosclerosis sex retinopathy, left ventricular hypertrophy, coronary heart disease, heart failure, cerebral arteriosclerosis and (or) history of cerebrovascular accident. Slow progression of symptoms a few gradually develop into renal failure, most perennial mild renal function damage and abnormal urine routine. Malignant high blood pressure, diastolic blood pressure should be more than 16 kpa (120 MMHG), accompanied by obvious cerebrovascular complications and rapid development, a large amount of proteinuria, often accompanied by hematuria, progressive renal function decline.
Second, the physical examination findings
General continuous blood pressure heighten (20.0/13 kpa, more than 150/100 MMHG); Some LIDS and/or lower limb edema, heart world expansion, etc.; Most arteriosclerosis sex retinopathy, when retinal hemorrhage and have stripes, flame cotton soft effusion, malignant renal arteriolar sclerosis diagnosis support. Associated with hypertensive encephalopathy can have corresponding neurological localization signs.
Third, auxiliary examination
(a) more for mild-to-moderate proteinuria, more than 24 hours of quantitative in 1.5 ~ 2.0 g; Microscopy visible part (red blood cells, white blood cells, less transparent tube type), can have blood in the urine; Early rising blood uric acid, urine NAG enzyme, beta 2 - MG increased, urine concentration - dilution dysfunction; Ccr slow decline, blood urea nitrogen, creatinine, increased. Renal tubular function damage much ahead of glomerular damage.
(2) of the imaging examination of kidney, there is no change more development cause renal failure kidney can appear when the varying degree reduces; Nuclide check the early renal function damage; Electrocardiogram (ecg) often hint left ventricular high voltage; Chest X-ray or echocardiographic indicate aortic stiffness, left ventricular hypertrophy or expanded.
(3) the clinical diagnosis of difficulties in the early renal biopsy should be done.
Fourth, the differential diagnosis

Except should all kinds of secondary hypertension, especially the type of chronic glomerulonephritis hypertension. Malignant renal arteriolar sclerosis with radical nephritis, systemic vasculitis disease such as phase identification.

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